cees dekker Things To Know Before You Buy
cees dekker Things To Know Before You Buy
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Nanotechnology presents An array of opportunities to contribute to biology. Right here I'll existing illustrations where nanofabrication – the ability to make confined structures with dimensions at will – is employed to examine the biophysics of solitary molecules and cells. I will current some examples from our lab:
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[Laughs] ‘It absolutely was surely an incredible possibility! At enough time, I used to be effectively conscious that it could go Incorrect and that I could come to be significantly less profitable, but I just overlooked that. Curiosity has generally been my strongest driving power. And fortuitously it all labored out.’
Our perform was speedily adopted up by Other folks, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 released their results on transistors constructed from one- and multi-walled carbon nanotubes in Utilized Physics Letters.
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SMC complexes can go Actual physical roadblocks larger than their ring measurement, indicating a nontopological mechanism for DNA loop extrusion
We use nanofabricated microfluidic structures to pattern spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks which evaluate the elemental purpose of spatial confinement for the molecular and mobile degree. Our assignments contain the next:
Dynamic ParB–DNA interactions initiate and retain a partition condensate for bacterial chromosome segregation
‘Yes, I fully grasp individuals ended up surprised at enough time. At the conclusion of the nineties, when I was in my https://www.ceesdekker.net forties, I used to be Professor of Molecular Electronics and I've to admit that it had turn into a bit bored, I didn’t find out A great deal any more. The sector went more into the appliance facet, how you could integrate nanotubes into Digital circuits.
Resolving the move size in condensin-pushed DNA loop extrusion identifies ATP binding given that the move-building process
‘The concept there is such a point being a commencing, a big bang, is currently an interesting signpost to look at that there was a creator. But much more typically, and on The idea of pure rationality, I also get there in a Christian interpretation of fact. An atheistic worldview is usually a naturalistic worldview: essentially, there are only atoms and organic forces that we will evaluate.
2006, first demonstration of molecular sorting within a lab over a chip applying biomotors; discovery of nanobubbles in strong-condition nanopores; and to start with estimate of electrokinetic Power conversion in the nanofluidic channel
Enable’s to start with look back in the meanwhile any time you made a decision to change your aim from superconductivity and nanotubes to biology at the conclusion of the nineteen nineties.
2004, discovery of latest physics in translocation of DNA by way of nanopores; very first experimental study of ions conduction in nanofluidic channels; initially electrochemistry with personal single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; initial electrical docking of microtubules on kinesin-coated nanostructures; to start with biophysics characterization on the mechanical Qualities of double-stranded RNA; and to start with solitary-molecule study of DNA translocation by a restriction-modification enzyme.